He is a co-principal investigator on the 50-year-old Vellore birth cohort. His department has the capacity to conduct hyperinsulinemic euglycaemic clamp studies, indirect caloriemetry and NMR Spectroscopy and has done state of the artwork around low birth weight and the metabolic syndrome and malnutrition modulated diabetes mellitus.

He has received grants to support research and outreach programmes from international and national agencies to the tune of several million rupees and is the recipient of the Yedanapalli Best Researcher award for the year 2009, the INCLEN young investigator of the year award 2004, the World India Diabetes Foundation Award for the year-2018, the Tamil Nadu Medical Council Award for the year-2022, the Molly and Thomas Bhanu, Best Teacher Award for the year, 2023 and the Dr MGR Medical University Faculty Award for Research for the year 2024.

He has given several orations (30) and talks, a talk at the US Congress (Capitol), the American Diabetes Association, the MS Ahuja Oration, the Subash Mukherjee oration and the Henry Rajaratnam Oration (at Sri Lanka and South Asian Federation of Endocrinology) and the Donald Mclarty Award lecture (At the East African Study group for diabetes in Tanzania).

In addition, he has given talks at meetings in over 35 countries over the world. He is guide for PhD under the MGR medical university, PhD guide under the Regional Biotechnology Institute, Phd co-guide in Karolinska, Sweden, inspector for the national board and examiner for the higher specialty examinations (DM and DNB) in endocrinology. He is a grant reviewer for the Indian Council of Medical Research, the ENDAC committee of the Drug Controller General of India, Department of Biotechnology and the Department of Science and Technology and was formerly on the Board of studies for research for the Dr MGR Medical University.

He has run more than 80 multinational and in-house designed clinical trials in Diabetes Mellitus. He was the organizing secretary of the Endocrine society of India Conference in Vellore in 2010 and the Winter symposium in 2007 and was a member of the Executive committee of the Endocrine Society of India. He has had research networks with several overseas universities which included Oxford, Copenhagen, Albert Einstein (New York), Monash, Melbourne and Karolinska Universities. He is an Encore Faculty member at the Melbourne University and a Phd Co-supervisor at the same university.

During his tenure as vice-principal research, he has enhanced the scope and the functioning of the institutional review board, got CMC, Vellore recognised as a centre for excellence under the Clinical Development Services Agency (CDSA), attempted to develop the processes of patenting and major the Annual research day in CMC, Vellore a major event.

He was Associate Director for Chittoor Campus at the CMC, Vellore and was involved in the active development of the CMC, Vellore Chittoor campus, an initiative to develop a 650-acre zone in the neighbouring state of Andhra Pradesh into a Broad specialty hospital with an impetus of evolving new dimensions in terms of educational aspects that CMC, Vellore has yet to venture into. Within a period of three years the college of nursing was initiated, the hospital infrastructure expanded and housing, radiology suite and hostels were created.

His was cofounder of the endocrinology department when it separated from the department of medicine in 1994 and was instrumental in contributing significantly to its growth. He has handled a significant clinical burden during that period and has established a state-of-the-art unit which handles large volumes of clinical work: about 90,000 patients per year, several subspecialty clinics: endocrine, integrated diabetes, young onset diabetes, pituitary, thyroid in addition to those started by his colleagues (menopause, metabolic bone disease).

He has played a significant role in the financial management of the department and handles the administration and governance of 70 staff within the department. He is a reviewer in several international journals and formerly on the editorial board of the journal: Clinical Endocrinology.

He was organizing secretary for the Endocrine Society of India Conference in 2010 (ESICON-2010, at Vellore, organizing secretary of the Winter Symposium in Endocrinology in 2007 at Vellore and the Organizing Chairperson for the Vellore Endocrinology International Congress in January 2025.

The Term “Type 5 Diabetes” which was coined at CMC Vellore as an alternative to Malnutrition modulated diabetes, by the International Diabetes Federation (IDF) president and formalized in Bangkok in April 2025, he is now co-chair on the IDF Working group for Type 5 Diabetes Mellitus.

He is the Principal coordinator for drawing the WHO GDM Guidelines of Timor-Leste and conducting a scoping review for 10 other countries including India, Bangladesh, Sri Lanka, Bhutan, Maldives, Myanmar, Nepal, Thailand, Democratic Peoples Republic of Korea (North Korea). He is chair for the DBT expert committee for Rare Genetic disorders.

His team and the department were awarded the prestigious: British Medical Journal South Asia Diabetology Team of the Year for 2015. His leadership was also instrumental in his team at the department of Endocrinology at CMC, Vellore being awarded in 2017, the Excellence in Patient care awards for the Royal College of Physicians- for outstanding work in advancing medical education and training. The Indian Council of Medical Research Collaborating Centre of Excellence (ICMR-CcoE)- 2024 for Diabetes Mellitus.