Karolinska-Vellore Type 1 Diabetes Collaboration            The Department of Endocrinology, Christian Medical College ,Vellore in joint collaboration with the Center for Molecular Medicine in Karolinska institute ,Stockholm,Sweden is working on immune etiology in the development of "Autoimmue diabetes". The group works on immune mediators in type 1 diabetes and Late autoimmune disease of the adult (LADA) , role of autoimmunity in gestational diabetes, Screening for genetic markers at birth and follow-up measurement of autoantibodies in the high risk children.  Projects: Genes of Innate Immunity (MICA, KIR, TLR) in autoimmunity Beta cell rest and recovery in Latent Autoimmune diabetes (LADA) Epidemiological studies of 'Diabetes in the Poor' in Asian Indians Genetics of Type 1 diabetes in Asian Indians Autoimmunity in Gestational diabetes and risk of autoimmune diabetes in their offsprings  Techniques:        1.Autoantibody analysis:                 i) ELISA                 ii) Radio ligand binding assay        2. Genotyping:                 i) SNP typing using Taqman                 ii) Sequencing using ABI sequncer                 iii) PCR-SSP        3. Immunohistochemistry        4. Luminex based cell sorting