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  • Dr. Fredrik Karpe, PhD, FRCP Reader in Metabolic Medicine

    Fredrik Karpe is a Welcome Trust senior clinical research fellow and an honorary consultant physician at Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Oxford UK. The focus of Dr Karpe's research is on human lipid and carbohydrate metabolism using integrative physiological and genomic approaches to understand the metabolic and cardiovascular complications of obesity and type 2 diabetes.

    A particular interest is the development and adoption of techniques for tissue-specific study of metabolic and physiological processes in vivo in humans. This often involves stable isotope tracer studies in combination with genomic/genetic approaches, sometimes using pharmacological agents to investigate tissue-specific metabolism and functional studies of human adipose tissue in vivo. Some of these studies are enabled by the establishment of the Oxford Biobank, which is a population-based screening of healthy participants in Oxfordshire allowing for a "recruit-by-genotype" approach. Dr Karpe's research is funded by the Wellcome Trust, British Heart Foundation and Diabetes UK. Dr Karpe is a member of the editorial boards of three international journals: 1. Atherosclerosis, 2. Nutrition, Metabolism and Cardiovascular disease and 3. International Journal of Obesity. His is President-Elect for the Royal Society of Medicine section on Lipids in Clinical Medicine. He visited the Department on January 2006.

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